Associate Professor, Biology Department
Phone: 814-871-7572
Office: Z 209
vagula001@gannon.edu

  • Courses Taught
  • Educational History
  • Professional Societies
  • Publications
  • Scholarship/Research
  • Service

Courses Taught

• Animal Physiology (BIOL 368)
• Animal Physiology Lab (BIOL 369)
• Cell Biochemistry (BIOL 373)
• Cell Biochemistry Lab (BIOL 374)
• Animal Form and Function (BIOL 124)
• Animal Form and Function Lab (BIOL 125)
• Molecular and Cellular Biology (BIOL 122)
• Molecular and Cellular Biology Lab (BIOL 123)
• Introductory Microbiology (BIOL 106)
• Introductory Microbiology Lab (BIOL 107)
• Human Biology (BIOL 104)

Educational History

B.S.  Osmania University, Hyderabad, India.
  Major: Biology
  GPA: 3.73/4.0

M.S.  Osmania University, Hyderabad, India
  Major: Zoology
  Specialization: Physiology
  GPA: 4.0/4.0

Ph.D. Osmania University, Hyderabad, India
  Area of Research: Physiological Toxicology

Professional Societies

• American Physiological Society (APS)
• Human Anatomy and Physiology Society (HAPS)
• Society of Toxicology (SOT)
• Federation of American Society of Experimental Biologists (FASEB)
• Society of Photographic Instrumentation Engineers,(SPIE) (Global Health, Military Medicine, Disaster Response, and Environmental Monitoring)
• Pennsylvania Academy of Science (PAS)

Publications

Books:

  • Vagula, M.C. Laboratory Exercises in Physiology, LAD Custom Publishing, Inc., Buford, GA, 2011.
  • Vagula, M.C. Experiments in Physiology, 2nd edition, LAD Custom Publishing, Inc., Buford, GA, 2010.
  • Vagula, M.C. A Laboratory Manual for Experimental Biochemistry, LAD Custom Publishing, Inc., Buford, GA, 2010.
  • Vagula, M.C. Experiments in Physiology, LAD Custom Publishing, Inc., Buford, GA, 2009.


Book Chapter

  • Vagula, M.C and Konieczko, E. (2012).  "Lipid Peroxidation and Polybrominated Diphenyl Ethers: A Toxicological Perspective." Chapter 24 in a book titled "Lipid Peroxidation" ISBN 980-953-307-143-0. InTech, Croatia.

Selected Peer Reviewed Publications:

  • Altaher, Morrison, A., Mastro, A., Vagula, M.C. (2014). Mapping the incidence pattern of some ailments and autoimmune diseases among young adults using GIS. HAPS Educator, 18(3) 23-25.
  • Vagula,M.C.(2014). Innovations in instructional technology to enhance learning experiences of upper level biology students
    HAPS Educator, 18(3) 29.
  • Nelatury, S. R and Vagula, M.C. (2014). Simulation Studies in Biochemical Signaling and Enzyme Reactions. Sensing Technologies for Global Health, Military Medicine, and Environmental Monitoring IV, edited by Šárka O. Southern, Mark A. Mentzer, Isaac Rodriguez-Chavez, Virginia E. Wotring, Proc. of SPIE Vol. 9112, 91121D • © 2014 SPIE. DOI: 10.1117/12.2053197.
  • Vagula, M.C. (2014) Regulation of Local Blood Flow. J Appl. Physiol 116:706-709, 2014; doi 10.1152/japplphysiol.01360.
  • Vagula, M.C., and Nelatury, S.R. (2013). Stiffness and hysteresis of tendons. J Appl Physiol. 2013 Feb 15;114(4):518-20
  • Vagula, M.C., Mastro A., and David L. Wessel. (2013) Cystic Fibrosis-Related Diabetes in Adolescents. US Pharm. 38(10)(Diabetes suppl):7-10.
  • Vagula,M.C., Rawding R.S (2012). Airway Hyperresponsiveness in Asthma and the Role of Airway Smooth Muscle. epublished in Journal of Applied Physiology and can be accessed at http://jap.physiology.org/content/early/2012/04/12/japplphysiol.00483.2012/reply#jap_el_38153
  • Vagula, M.C., Nelatury, C.F (2012). Nuances in the Physiological Responses during Hypobaric Hypoxia and Normobaric Hypoxia. Journal  Applied Physiology 112, 1794; doi:10.1152/japplphysiol.00356
  • Vagula, M.C., Vartak, M and Tallmadge, W. (2012). GC-MS analysis of polybrominated diphenyl ethers in the Lake Erie.  Published in the proceedings of SPIE, Sensing Technologies for Global Health, Military Medicine, Disaster Response, and Environmental Monitoring II; Proc. of SPIE Vol. 8371, 83711G 1-6 • © 2012 SPIE
  • Vagula, M.C., Rawding, R (2012). Epigenetic Factors and ACE Gene I/D Polymorphism in Endurance Physiology.  Journal of Applied Physiology 112: 1084–1085.
  • Vagula, M.C., Nelatury C.F. (2011). Physiological adaptations and optimal control in birds which fly at high altitudes. Journal  Applied Physiology 111:1520-1524. doi:10.1152/japplphysiol.01117.2011
  • Vagula, M.C., Kubeldis N., Nelatury C.F. (2011) Effects of BDE- 85 on the Oxidative Status and Nerve Conduction in Rodents. International journal of toxicology 30(4) 428-434.
  • Vagula M.C, Kubeldis N., Nelatury, C.F. (2011) Environmental Monitoring of brominated flame retardants. Published in the proceedings of Sensing Technologies for Global Health, Military Medicine, Disaster Response, and Environmental Monitoring; and Biometric Technology for Human Identification VIII, Proc. of SPIE Vol. 8029, 80291J • © 2011 SPIE • CCC code: 0277-786X/11/$18 • doi: 10.1117/12.887127
  • Vagula M.C. (2011) The express need for accurately measuring physical activity. Journal of Applied Physiology. 111:(2) 608; 011.   Doi:10.1152/japplphysiol.00650.2011
  • Vagula, M.C., Nelatury, C.F. (2010). Another voice in support of cool thinking (on "Humans do/do not demonstrate selective brain cooling during hyperthermia."). Published in the Journal of Applied Physiology February 2011, 110:575-580. doi:10.1152/japplphysiol.01375.2010
  • Vagula, M.C. (2010).  Additional factors influencing marathon times. Epublished in Journal of Applied Physiology. http://jap.physiology.org/content/early/2010/08/05/japplphysiol.00563.2010.abstract/reply#jap_el_6568
  • Turner, R.B., Vagula, M.C., Devi,S.S.(2009) “Osteoporosis: an understated complication of diabetes,”  US Pharmacist. Vol. 34 No. 5 (Diabetes and Pharmaceutical care): pp.14-16, 2009.
  • Vagula, M. C. & Devi, S.S. (2008). Hepatotoxicity of Antidiabetic Drugs. US  Pharmacist (Diabetes suppl) 33(5), 3-9.

Selected Presentations (Oral and Posters) at Regional Conferences:

  • Nelatury, C.F., Vagula, M.C., and Nelatury, S.R., “Estimation of enzyme parameters using MATLAB program,” Presented at the Undergraduate Research, Scholarship, and Creativity Celebration, Gannon University, April 2009.
  • Nelatury, C. F., Kubeldis, N., & Vagula, M.C. (2009). In Vitro Studies on the Conduction Velocity in Rat Sciatic Nerve following Exposure to Penta BDE and Deca BDE. Poster presented on November 5th at 5th Annual Research Symposium, Regional Science Consortium, Tom Ridge Environmental Center, Erie, PA.
  • Reynolds, J., Nelatury, C. F., & Vagula, M.C. (2009). Alterations in Glucose Absorption across the Small Intestines of Rats Exposed to Penta and Deca brominated diphenyl ethers (PBDEs). Presented on November 5th at 5th Annual Research Symposium, Regional Science Consortium, Tom Ridge Environmental Center, Erie, PA.
  • Kubeldis, N.R., Nelatury, C.F., Reynolds, J., & Vagula, M.C. (2010). Invitro Studies in Glucose Absorption across the Small Intestine and Conduction Velocity in the Sciatic Nerve of Rats following Exposure to Penta- and Deca-brominated diphenyl ether. Presented on April 17th at 31st Annual Western PA Biology Symposium, Geneva College. PA.
  • Kubeldis, N., Nelatury, C.F. and Vagula, M.C. (2011) Lipid Peroxidation and Antioxidant Enzyme Activities in BDE-85 Treated Mice. Sigma Xi Undergraduate Research and Creative Accomplishment Conference, April 16th 2011
  • Kubeldis, N., Nelatury, C.F. and Vagula, M.C. (2011) BDE-209 Induced Alterations in the Oxidative Status of Mice Tissues. Sigma Xi Undergraduate Research and Creative Accomplishment Conference, April 16th 2011.
  • Moore, J and Vagula M. C.(2011) BDE-85 induced toxicity in Human Umbilical Vein Endothelial cells. Sigma Xi Undergraduate Research and Creative Accomplishment Conference, April 16th 2011.
  • Moore J and Vagula M. C. (2011) Cytotoxic and Genotoxic Effects of BDE-209 in Human Umbilical Vein Endothelial cells. Sigma Xi Undergraduate Research and Creative Accomplishment Conference, April 16th 2011.

Published Absracts / Poster  Presentations  at National Conferences:

  • Kubeldis N R and Vagula,M.C. (2010).Oxidative Status of the Tissues of Mice following Exposure to Deca BDE (BDE-209). Presented on Aug 7th at 2010- APS Intersociety Meeting Global Change Global Science: Comparative Physiology in a Changing World August 4-7, 2010, Westminster, Colorado.
  • Kubeldis N.R, Nelatury C.F, and Vagula M.C.(2011) Neurological and biochemical toxic profile of BDE-85. Experimental Biology- 2011 April 9th - 13th, Washington D.C
  • .Kubeldis N.R, Nelatury C.F, and Vagula M.C. (2011)In vitro and in vivo toxicity studies of BDE-209. Experimental Biology- 2011 April 9th - 13th, Washington D.C.
  • Vagula M.C, Kubeldis N.R, Nelatury C.F.(2011) Environmental Monitoring of brominated flame retardants. SPIE Conference: “Sensing Technologies for Global Health, Military Medicine, Disaster Response, and Environmental Monitoring”, April 26th  2011, Florida. 
        

Scholarship/Research

Ever since I joined my Masters program I particularly became interested in physiology and biochemical processes of the body. During that time, in the city where I grew, environmental pollution was a serious concern. After graduating my MS (with a GPA 4.0/4.0 and as the valedictorian), I joined my professor of physiology, Dr. S.L.N. Reddy, to work on toxic effects of lead on the physiological and biochemical processes of fresh water fish. I did an extensive research on the toxicity of lead and published several research papers. Later I continued my lead toxicity work on mice in the same laboratory. After coming to Gannon University, Erie, PA, I began teaching Physiology, Biochemistry and related courses. Also I wanted to resume my research in toxicology and physiology. The growing concern arising from the toxicological role of certain materials used as fire retardants like PBDEs caught my attention. I began my work in this area and mentored students in this research project.  I first started the toxicological work on PBDEs by observing the influence of PBDEs on the sciatic nerve conduction velocity and intestinal absorption of glucose in rats. Later the work was extended to study the oxidative damage caused by these compounds.  Oxidative damage is responsible for slow degeneration of the nervous system and body. This damage is also responsible for aging and age associated diseases. My next phase of research will focus on cell cycle regulating gene expression following PBDE exposure in human cells.

Service

  • Member, Affirmative Action Committee, 2014-
  • Member, College Academic Affair Committee 2011-2014
  • Member,  Student Success Committee, 2011-2014
  • Member, Middle States Self Study Report Working Group- Standard 14
  • Member, Safety Committee, 2011-2014
  • Member, Library Committee Member 2008-2011