Assistant Professor, Biology Department
Phone: 814-871-5693
Office: Z 211
mattinso001@gannon.edu

  • Biography
  • Courses Taught
  • Educational History
  • Professional Societies
  • Publications
  • Scholarship/Research
  • Service

Biography

I'm originally from Cleveland, but spent my undergraduate years in Columbus at The Ohio State University.  After graduation, I continued my studies at the University of Kentucky where I completed my dissertation research in neurobiology.  I also pursued the Graduate Certificate in Anatomical Sciences at UK, thus developing my love of teaching anatomy.

I love being a faculty member at Gannon University.  I like the close-knit community feel of the college, and the culture and attitude of Erie remind me a lot of growing up in Cleveland.    

When I'm not in class or in the lab, I like to spend my time gardening, sewing, reading, and cheering on the Buckeyes!  My husband, Jason, is also a graduate of The Ohio State University, and you can find us glued to the television on Saturdays during football season. 

Courses Taught

  • Essentials of Anatomy & Physiology 1 (BIOL 108)
  • Essentials of Anatomy & Physiology 1 Lab (BIOL 109)
  • Essentials of Anatomy & Physiology 2 (BIOL 110)
  • Essentials of Anatomy & Physiology 2 Lab (BIOL 111)
  • Human Gross Anatomy (BIOL 365)
  • Human Gross Anatomy Lab (BIOL 366)

Educational History

  • The Ohio State University, B.S. in Psychology, Undergraduate Senior Honors Thesis Title: An Innovative Method for Measuring Cortical Acetylcholine Release in Animals on a Second-by-Second Time Scale, Advisor:  Dr. John P. Bruno, 2006
  • University of Kentucky, Ph.D., Department of Anatomy and Neurobiology, Dissertation Title: Dynamic L-Glutamate Signaling in the Prefrontal Cortex and the Effects of Methylphenidate Treatment, Advisor: Dr. Greg A. Gerhardt, 2012

Professional Societies

  • American Association of Anatomists (AAA)
  • American Association of Clinical Anatomists (AACA)
  • Society for Neuroscience (SFN)

Publications

Publications

  • Burmeister, J.J., F. Pomerleau, P. Huettl, C.R. Gash, C.E. Werner, J.P. Bruno, and G.A. Gerhardt.  2008.  Ceramic-based multisite microelectrode array for simultaneous measures of choline and acetylcholine in CNS. Biosens Bioelectron. 23(9), 1382-9.
  • Mattinson, C.E., J.J. Burmeister, J.E. Quintero, F. Pomerleau, P. Huettl, and G.A. Gerhardt.  2011.  Tonic and phasic release of glutamate and acetylcholine neurotransmission in sub-regions of the rat prefrontal cortex using enzyme-based microelectrode arrays. J Neurosci Methods. 202(2), 199-208.

 

Published Abstracts

  • C.E. Werner, J.J. Burmeister, C.R. Gash, F. Pomerleau P.  Huettl, J.P. Bruno, and G.A. Gerhardt. Second-by-second microelectrode array measurements of acetylcholine. 12th annual meeting – Institute of Biological Engineering. St. Louis, MO, 2007.
  • C.E. Werner, J.J. Burmeister, C.R. Gash, F. Pomerleau P.  Huettl, J.P. Bruno, and G.A. Gerhardt. Second-by-second microelectrode array measurements of acetylcholine release and uptake in cortex and striatum. 37th annual meeting - Society for Neuroscience. San Diego, CA, 2007.
  • C.E. Werner, J.J. Burmeister, C.R. Gash, F. Pomerleau, P. Huettl, J.P. Bruno, and G.A. Gerhardt.  Regional analysis of acetylcholine neurotransmission in rat prefrontal cortex and striatum.  Monitoring Molecules in Neuroscience. 12th International Conference on In Vivo Methods. Vancouver, British Columbia, Canada, 2008.
  • C.E. Mattinson, J.E. Quintero, F. Pomerleau, P. Huettl, and G.A. Gerhardt. Regional depth analysis in rat PFC of glutamate neurotransmission in vivo: effects of anesthetics and diurnal rhythms.  Monitoring Molecules in Neuroscience. 13th International Conference on In Vivo Methods. Brussels, Belgium, 2010.
  • C.E. Mattinson, J.E. Quintero, F. Pomerleau, P. Huettl, and G.A. Gerhardt.  Diurnal recordings of second-by-second measurements of tonic and phasic glutamate release in the prefrontal cortex of awake rats using microelectrode arrays.  41st annual meeting – Society for Neuroscience.  Washington, D.C., 2011.
  • P.E.A. Glaser, C.E. Mattinson, J.S. Beckmann, M.T. Bardo, and G.A. Gerhardt.  The effects of methylphenidate on glutamate signaling in the prefrontal cortex of awake freely-moving rats.  Monitoring Molecules in Neuroscience.  14th International Conference on In Vivo Methods.  London, England, 2012.
  • O.M. Littrell, C.E. Mattinson, P. Huettl, F. Pomerleau, J.E. Quintero and G.A. Gerhardt.  Defining glutamate transients in the awake rat: analysis of sub-second in vivo recordings.  Monitoring Molecules in Neuroscience.  14th International Conference on In Vivo Methods.  London, England, 2012.

Scholarship/Research

My research focuses on neutrotransmitter signaling in the mammalian brain.  I am interested in aging, and specifically, changes in neurotransmitter levels associated with aging.  It is important to understand what happens to neurotransmission during the "normal" aging process, so that we can separate out those changes from any changes associated with pathologies (e.g., Alzheimer's disease, Parkinson's disease). 

The area of the brain I focus on is the striatum.  This area of the brain is important for motor movements as well as spatial learning and memory.  One of the major regulatory neurons of the striatum is the cholinergic interneuron.  These neurons use acetylcholine to modulate dopamine as well as other neurotransmitter systems in the striatum.

My research uses behavioral tasks and neurotransmitter measurements to correlate changes in behavoir with changes in neurotransmitter levels in a model of aging.  I measure choline in the striatum using microelectrode array technology.  This technique provides the advanced spatial and temporal resolution necessary to characterize in vivo choline levels in the striatum.  

From a translational perspective, my research is important because a better understanding of changes in neurotransmitter levels associated with aging (and the potential effects of those changes on behavior) can contribute to improved treatments for neuropathologies.   

Service

  • Advisor of Gamma Sigma Sigma service sorority
  • University Student Conduct Committee
  • University Athletic Committee
  • Morosky College of Health Professions and Sciences Academic Affairs Committee