Keith Michael Krise is an assistant professor of chemistry. At Gannon University, his primary areas of teaching are general and inorganic chemistry. Krise joined the Gannon University Department of Chemistry and Biochemistry in 2014.
Krise earned is Ph.D. in Chemistry at the Pennsylvania State University in 2011. As a graduate research assistant, Krise first engaged in interdisciplinary research on plasma membrane nanostructure and the role of cholesterol-rich domains in cell signaling events and, subsequently, studied the effects of microviscosity, bound water, and protein mobility on the radiolysis and sonolysis of a protein hydrogel (hen albumen) that mimicked mucous membranes.
At Gannon University, Krise has continued to engage in research, often involving undergraduate students, in the area of sonochemistry and nanoparticle synthesis, characterization, and application. Krise's projects combine elements of inorganic, physical, and analytical chemistry as well as biochemistry and molecular biology. The multi-disciplinary nature of his scholarly work support undergraduates in both the Department’s chemistry and biochemistry programs.
Outside the classroom and laboratory, Dr. Krise, his wife, and children enjoy taking advantage of all that Erie and the surrounding region has to offer.
Dr. Krise's current research interests involve elucidating the effects that high-frequency ultrasound have on the structure and function of (1) enzymes and other bioorganic/bioinorganic molecules and (2) nanomaterials. In particular, he is interested in determining the role of free-radical species generated during sonication in the possible deactivation or activation of enzymes and the structure and properties of nanomaterials.
Dr. Krise is also involved in several collaborative projects:
1. Drs. Betty Jo Chitester (Gannon Unversity, Department of Chemistry and Biochemistry) and Krise are studying the antibacterial properties of metal nanoparticles. These projects combine elements of inorganic, physical, and analytical chemistry as well as biochemistry and molecular biology.
2. Drs. Betty Jo Chitester, Weslene Tallmadge (Gannon University, Department of Chemistry and Biochemistry), and Krise are examining the lead content in spices obtained from bulk food stores.
3. Drs. Christine Saber (Gannon Unversity, Department of Chemistry and Biochemistry) and Krise are working with the Erie Water Works to assess microcystin levels at various stages of the water treatment process.
In addition, Dr. Krise has interests in pedagogically-oriented research including the development of mastery-based learning modules, designing flipped-classroom courses and materials, and development of novel laboratory exercises for experimental general, physical, and inorganic chemistry courses.