Faculty Profile: Sarah J. Ewing

Courses Taught

• Molecular and Cellular Biology (BIOL 122)
• Molecular and Cellular Biology Lab (BIOL 123)
• Biology of Cancer (BIOL 495)
• Cellular Biochemistry (BIOL 373)

Educational History

• Ph.D. in Comparative Biomedical Sciences, December 2007 North Carolina State University, Raleigh, NC. Dissertation: "C/EBPbeta represses p53 to promote cell survival downstream of DNA damage independent of oncogenic Ras and p19Arf". Advisor: Dr. Robert C. Smart.
• B.S. in Biology, minor in Chemistry, May 2001, Penn State Behrend, The Erie College, Erie, PA. University Schreyer Scholar Thesis:  "Genetic Diversity in Black Cherry (Prunus serotina) Using Microsatellite DNA Markers". Advisor: Dr. Michael Campbell.

Professional Experience

• Assistant Professor of Biology, Gannon University, Erie, PA (2009 - Present)
• Director of Pre-Professional Programs, Gannon University, Erie, PA (2009 - Present)
• Lecturer in Biology, Penn State Behrend, the Erie College, Erie, PA (2007 - 2009)

Professional Societies

• Sigma Xi, The Scientific Research Society (Northwest Pennsylvania Chapter)
• Society of Toxicology (SOT)
• American Association for the Advancement of Science (AAAS)
• American Society for Cell Biology (ASCB)
• National Association for Biology Teachers (NABT)
• National Association of Advisors for the Health Professions (NAAHP)
• Northeast Association of Advisors for the Health Professions (NEAAHP)

Publications

Peer Reviewed Articles:

• Ewing, S. J., Zhu, S. Zhu, F. House, J. S. & Smart, R. C. (2008). C/EBPb represses p53 to promote cell survival downstream of DNA damage independent of oncogenic Ras and p19Arf. Cell Death and Differentiation, 15(11), 1734-1744.
• Yoon, K., Zhu, S., Ewing, S.J., Smart, R.C. (2007) Decreased survival of C/EBPb-deficient keratinocytes is due to aberrant regulation of p53 levels and function. Oncogene, (26):360-367. 
• Shim, M., Powers, K.L., Ewing, S.J., Zhu, S., Smart, R.C.  (2005) Diminished expression of C/EBPa in skin carcinomas is linked to oncogenic Ras and re-expression of C/EBPa in carcinoma cells inhibits proliferation. Cancer Res, 65(3):861-867.
• Moorefield, K.S., Fry, S.J., Horowitz, J.M.  (2004) Sp2 DNA-binding activity and trans-activation are negatively regulated in mammalian cells. J Biol Chem, 279(14):13911-13924.

Book Chapters:

• Smart, R.C., Ewing, S.J., & Loomis, K.D. (2008). Carcinogenesis.  In R. C. Smart & E. Hodgson (Eds.), Molecular and biochemical toxicology (pp. 537-586). New York: John Wiley and Sons.

Published Abstracts:

• Ewing, S.J., Zhu, S., Smart, R.C. (2007) C/EBPb regulates p53 downstream of DNA damage independent of oncogenic stress and p19Arf.  American Association for Cancer Research Annual Meeting 2007, April 2007, Los Angeles, CA.
• Fry, S.J., Campbell, M.A. (2001) Determining Genetic Diversity in Black Cherry, Prunus serotina, using Microsatellite Markers. International Plant and Animal Genomes Conference, January 2001, San Diego, CA.

Service

• Library and Learning University Standing Committee Member (Fall 2012 - Present)
• College Academic Affairs Committee Member for Morosky College of Health Professions and Sciences (Fall 2011 - Present)
• Student Conduct University Standing Committee Member (Fall 2010 - Present)