Instructor, Biology Department
Phone: 814-871-5576
Office: Z 330A
cabarcas002@gannon.edu

  • Courses Taught
  • Educational History
  • Professional Societies
  • Publications

Courses Taught

• BIOL 122 - Molecular and Cellular Biology Lecture
• BIOL 123 – Molecular and Cellular Biology Lab
• BIOL 125 - Animal Form and Function Lab
• BIOL 368 - Animal Physiology Lecture
• BIOL 369 - Animal Physiology Lab

Educational History

National Institute of Health, National Cancer Institute, Frederick, MD,  Cancer Research Training Awardee, Postdoctoral Fellow, 2009-2011

St. John's University, Queens, NY,  Ph.D in Biology, Dissertation Title:   "The negative regulation of RNA polymerase III transcription in cancer cells", 2009  

St. John's University, Queens, NY, MS in Biology, 2007

High Point University, High Point, NC, BS in Biology, 2004

 

Professional Societies

  • American Society for Cell Biology (ASCB)
  • Society for Advancement of Hispanics/Chicanos & Native Americans in Science (SACNAS)
  • National Postdoctoral Association (NPA)
  • Association for Women in Science (AWIS)
  • American Association for Cancer Research (AACR)
  • American Society for Biochemistry and Molecular Biology (ASBMB)

Publications

  • Cabarcas SM, Mathews LA, Sun L, Thomas SB, Zhang X and Farrar WL.  The differentiation of pancreatic tumor initiating cells by vitronectin can be blocked by Cilengitide.  Pancreas:  Accepted.   
  • Mathews LA, Cabarcas SM, Hurt EM (Eds).  Book:  DNA Repair of Cancer Stem Cells.  Springer:  2013.  (http://www.springer.com/biomed/book/978-94-007-4589-6)
  • Kang M, Baker A, Dextras C, Cabarcas SM, Young MR, Colburn NH.  Targeting of non-canonical Wnt5a signalling by AP-1 blocker dominant negative jun when it inhibits skin carcinogenesis. Genes Cancer. 2012 Jan;3(1):37-50
  • Sun L, Yang A, Cabarcas SM, Mathews LA, Farrar W.  Perspectives and Challenges in Epigenetic Therapy: DNA Methylation in Cancer Stem Cells.  Book Chapter in:  DNA Methylation: Principles, Mechanisms and Challenges”.  Nova Science Publisher:  2013. (https://www.novapublishers.com/catalog/product_info.php?products_id=37900) 
  • Cabarcas SM, Thomas S, Zhang X, Cherry JM, Thomas S, Yerramilli S, Lader E, William WL and Hurt EM.  (2011) The role of upregulated miRNAs and the identification of novel mRNA targets in prostatospheres. Genomics 2012 Feb;99(2):108-17.
  • Sun L, Cabarcas SM, Farrar WL.  Radioresistance and Cancer Stem Cells: Survival of the Fittest.  J Carcinogene Mutagene. 2011.  S1:004. doi:10.4172/2157-2518.S1-004
  • Cabarcas SM, Mathews L, Farrar WL.  The Cancer Stem Cell Niche – there goes the neighborhood? Int J Cancer.  2011 Nov 15; 129(10):2315-27.
  • Mathews L, Cabarcas SM, Hurt E, Zhang X, Jaffee E, Farrar WL.  Increased expression of DNA repair genes in invasive human pancreatic cancer cells. Pancreas. 2011 Jul;40(5):730-9.
  • Cabarcas SM and Schramm L.  RNA polymerase III transcription and cancer:  the Brf2 connection.  Mol Cancer. 2011 Apr 25;10(1):47.
  • Crea F, Hurt E, Mathews LA, Cabarcas SM, Sun L, Marquez VE, Danesis R, Farrar WL.  Pharmacologic disruption of Polycomb Repressive Complex 2 inhibits tumorigenicity and tumor progression in prostate cancer.  Mol Cancer. 2011 Apr 18; 10(1):40
  • Mathews L, Cabarcas SM, Farrar WL. DNA repair:  The culprit for tumor initiating cell survival? Cancer Metastasis Rev.  2011 Jun; 30(2):185-97
  • Cabarcas SM, Hurt E, Farrar WL.  Defining the Molecular Nexus of Cancer, Type 2 Diabetes and Cardiovascular Disease.  2010 Curr Mol Med. Nov; 10(8):744-55
  • Cabarcas S, Watabe K, Schramm L.  Inhibition of U6 snRNA transcription by PTEN.  Online J Biol Sci. 2010 Sep 30; 10(3):114-125.
  • Cabarcas S, Jacob J, Veras I, Schramm L. Differential expression of the TFIIIB subunits Brf1 and Brf2 in cancer cells. BMC Mol Biol.  2008 Aug 12; 9:74.
  • Jacob J, Cabarcas S, Veras I, Zaveri N, Schramm L. The green tea component EGCG inhibits RNA polymerase III transcription. Biochem. Biophys. Res. Commun. 2007. 360 (4), 778-83.
  • Rollins J, Veras I, Cabarcas S, Willis I, Schramm L. Human Maf1 negatively regulates RNA polymerase III transcription via the TFIIIB family members Brf1 and Brf2. Int. J. Biol. Sci. 2007 May 1;3(5):292-302.